Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000761
Members of this Pool
Members of control pools
POOL000760
Last modified: 10/Sep/2021
Results
Publication
Cerritelli SM, Iranzo J, Sharma S, Chabes A, Crouch RJ, Tollervey D, El Hage A: High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase., Nucleic Acids Res, 2020

PubMed PMCID
Value 50
Dimension pmol/108 cell
Error (standard error of the mean) 5.26
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain BY4741
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Remarks to measurement type Watt et al. 2016
Growth conditions N/A
Treatment
Genes and Proteins
Gene name RNR1
Gene identifier 856801
Protein name ribonucleotide reductase
Protein identifier P21524
Genetic manipulation/variation mutation
Mutation in protein RNR1 gene is tagged (3HA-RNR1) and is under the control of the PGAL1/10 promoter