2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000729
Members of this Pool
Members of control pools
POOL000727
Last modified: 10/Sep/2021
Results
Publication
Meli M, Tolomeo M, Grifantini M, Mai A, Cappellacci L, Petrelli R, Rotili D, Ferro A, Saiko P, Szekeres T, Dusonchet L: Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells., Int J Oncol, 2011

PubMed
Value 40.3
Dimension %
Error (standard error of the mean) 14.9
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication HL-60 acute promyelocytic cell line
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions logarithmically growing HL60 cells (0.5 x 106 per ml) were incubated with 0.4 μM TSA
Treatment
Drug/stress type drug
PubChem 444732
Applied drug trichostatin A
Genes and Proteins
No genes or proteins manipulated.