Results
Publication	Santinon G, Brian I, Pocaterra A, Romani P, Franzolin E, Rampazzo C, Bicciato S, Dupont S: dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene-induced senescence., EMBO J, 2018 PubMed PMCID
Value	39.5
Dimension	pmol/106 cell
Error	Error not provided.
Data presentation in publication	diagram

Source
Source organism	human (Homo sapiens) Taxonomy 9606
Sample source	cell line
CLO Cell line name	WI 38 cell (CLO:0009591)
Cell line/type as in publication	WI38 human fibroblasts
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	methanol
Remarks to measurement type	radioactive Ferraro et al. 2010
Growth conditions	N/A

Treatment
Treatment details/effects	infected with RAS and YAP 5SA expressing virus vector; mutation of all five serines to alanines (5SA) generates a highly tumorigenic, constitutively active YAP mutant resistant to inhibition by the Hippo pathway.

Genes and Proteins
Gene name	HRAS
Gene identifier	3265
Protein name	GTPase Hras
Protein identifier	P01112
Genetic manipulation/variation	extrachromosomal expression of mutant protein
Mutation in protein	G12V
Gene name	WWTR1
Gene identifier	25937
Protein name	WW domain-containing transcription regulator protein 1
Protein identifier	Q9GZV5
Genetic manipulation/variation	extrachromosomal expression of mutant protein
Mutation in protein	5SA mutant (tumorigenic)