DNTP002828
dTTP
dNTP Pool | |
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Pool identifier | POOL000712 |
Members of this Pool |
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Members of control pools |
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POOL000704 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Kramata P, Downey KM: 9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis.,
Mol Pharmacol, 1999
PubMed |
Value | 146 | Dimension | % |
Error | Error not provided. |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
CLO Cell line name | CCRF-CEM cell (CLO:0002334) |
Cell line/type as in publication | T-lymphoblastoid cell line CCRF-CEM |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | acid extraction |
Remarks to measurement type | radioactive Sherman and Fyfe 1989 |
Growth conditions | 24 h incubation with 1 to 100 μM nucleotide analogs |
Treatment | |
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Drug/stress type | drug |
PubChem | 64988 |
Applied drug | 9-(2-phosphonylme- thoxyethyl)-2,6-diaminopurine (PMEDAP) |
Treatment details/effects | 10 μM PMEDAP |
Genes and Proteins | |
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No genes or proteins manipulated. | |