2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000706
Members of this Pool
Members of control pools
POOL000704
Last modified: 10/Sep/2021
Results
Publication
Kramata P, Downey KM: 9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis., Mol Pharmacol, 1999

PubMed
Value 184
Dimension %
Error Error not provided.
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name CCRF-CEM cell (CLO:0002334)
Cell line/type as in publication T-lymphoblastoid cell line CCRF-CEM
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type radioactive Sherman and Fyfe 1989
Growth conditions 24 h incubation with 1 to 100 μM nucleotide analogs
Treatment
Drug/stress type drug
PubChem 135409438
Applied drug 9-(2-phosphonylmethoxyethyl)guanine (PMEG)
Treatment details/effects 3 μM PMEG
Genes and Proteins
No genes or proteins manipulated.