2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000659
Members of this Pool
Members of control pools
POOL000670
Last modified: 10/Sep/2021
Results
Publication
Wilson PK, Szabados E, Mulligan SP, Christopherson RI: Comparative effects of cladribine, fludarabine and pentostatin on nucleotide metabolism in T- and B-cell lines., Int J Biochem Cell Biol, 1998

PubMed
Value 2
Dimension μM
Error Error not provided.
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name Raji cell (CLO:0008734)
Cell line/type as in publication Raji
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions 37°C in RPMI 1640 medium; cell extracts were oxidised
Treatment
Drug/stress type drug
PubChem 30751
Applied drug Fludarabine phosphate (F-Ara-AMP)
Treatment details/effects 24 hours drug treatment; inhibit DNA polymerase alpha, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis
Genes and Proteins
No genes or proteins manipulated.