2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000628
Members of this Pool
Members of control pools
POOL000625
Last modified: 10/Sep/2021
Results
Publication
Wilson PK, Szabados E, Mulligan SP, Christopherson RI: Comparative effects of cladribine, fludarabine and pentostatin on nucleotide metabolism in T- and B-cell lines., Int J Biochem Cell Biol, 1998

PubMed
Value 12.53
Dimension μM
Error Error not provided.
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name CCRF-CEM cell (CLO:0002334)
Cell line/type as in publication CCRF-CEM leukemia cell line
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions 37°C in RPMI 1640 medium; cell extracts were oxidised
Treatment
Drug/stress type drug
PubChem 30751
Applied drug Fludarabine phosphate (F-Ara-AMP)
Treatment details/effects 3 hours drug treatment; inhibit DNA polymerase alpha, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis
Genes and Proteins
No genes or proteins manipulated.