2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000561
Members of this Pool
Members of control pools
POOL000559
Last modified: 10/Sep/2021
Results
Publication
Fu Y, Long MJC, Wisitpitthaya S, Inayat H, Pierpont TM, Elsaid IM, Bloom JC, Ortega J, Weiss RS, Aye Y: Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3., Nat Chem Biol, 2018

PubMed PMCID
Value 1.02
Dimension fold change
Error (standard deviation) 0.15
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name Tango cell (CLO:0037271)
Cell line/type as in publication HEK 293T
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Sherman and Fyfe
Growth conditions N/A
Treatment
Treatment details/effects contains RRM1 +NLS vector, induced with tetracycline
Genes and Proteins
Gene name RRM1
Gene identifier 6240
Protein name RIR1
Protein identifier P23921
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein contains additional NLS