DNTP002142
dGTP
dNTP Pool | |
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Pool identifier | POOL000551 |
Members of this Pool |
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Members of control pools |
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POOL000548 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Rentoft M, Lindell K, Tran P, Chabes AL, Buckland RJ, Watt DL, Marjavaara L, Nilsson AK, Melin B, Trygg J, Johansson E, Chabes A: Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance.,
Proc Natl Acad Sci U S A, 2016
PubMed PMCID |
Value | 8.4586 | Dimension | fold change |
Error (unspecified) | 0.6 |
Relative compared to | total NTP pool in untreated HCT116 cells |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
CLO Cell line name | HCT 116 cell (CLO:0003665) |
Cell line/type as in publication | HCT116 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Remarks to measurement type | Chabes |
Growth conditions | HCT116 cells incubated in the presence of 50 μM thymidine and 20 μM deoxyadenosine for 20 h, after which an additional 50 μM thymidine and 20 μM were added. dNTP pools were measured after 4 h |
Treatment | |
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Drug/stress type | drug |
PubChem | 13730 , 5789 |
Applied drug | deoxyadenosine, thymidine |
Genes and Proteins | |
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No genes or proteins manipulated. | |