Results
Publication	Rentoft M, Lindell K, Tran P, Chabes AL, Buckland RJ, Watt DL, Marjavaara L, Nilsson AK, Melin B, Trygg J, Johansson E, Chabes A: Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance., Proc Natl Acad Sci U S A, 2016 PubMed PMCID
Value	3.26
Dimension	(dNTP/ tot. NTP)x100
Error (interquartile range)	2.97; 3.46
Data presentation in publication	diagram

Source
Source organism	mouse (Mus musculus) Taxonomy 10090
Animal strain	SAMHD1−/− homozygous
Sample source	embryo
Tissue type	E13.5 embryo
Compartment	whole cell

Experiment Details
Measurement type	HPLC-UV
Extraction method	acid extraction
Remarks to measurement type	Chabes
Growth conditions	N/A

Treatment
Treatment details/effects	The four tested mutations—V133I, A338T, R366H, and D497Y—negatively affected SAMHD1 dNTPase activity in vitro

Genes and Proteins
Gene name	Samhd1
Gene identifier	56045
Protein name	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Protein identifier	Q60710
Genetic manipulation/variation	mutation
Mutation in protein	V133I, A338T, R366H, and D497Y