Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000539
Members of this Pool
Members of control pools
POOL000536
Last modified: 10/Sep/2021
Results
Publication
Watt DL, Buckland RJ, Lujan SA, Kunkel TA, Chabes A: Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools., Nucleic Acids Res, 2016

PubMed PMCID
Value 16
Dimension fold change
Error (standard error of the mean) 1.066
Relative compared to control
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Remarks to measurement type Chabes
Growth conditions Diploid cells passage 1
Treatment
Genes and Proteins
Gene name rnr1
Gene identifier 856801
Protein name Ribonucleoside-diphosphate reductase large chain 1
Protein identifier P21524
Genetic manipulation/variation mutation
Mutation in protein Y285A
Gene name msh2
Gene identifier 854063
Protein name DNA mismatch repair protein MSH6
Protein identifier P25847
Genetic manipulation/variation mutation
Mutation in protein knock-out