2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000507
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Itsko M, Schaaper RM: dGTP starvation in Escherichia coli provides new insights into the thymineless-death phenomenon., PLoS Genet, 2014

PubMed PMCID
Value 5.3
Dimension %
Error (standard deviation) 0.3
Relative compared to ATP
Data presentation in publication numerical
Source
Source organism E. coli (Escherichia coli)
Taxonomy 562
Bacterial or fungal strain MG1655
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method methanol
Growth conditions dNTP pools in strains grown with hypoxanthine
Treatment
Treatment details/effects The optA1 allele of dgt is a promoter-up mutation, which increases gene expression by as much as 50-fold.
Genes and Proteins
Gene name dgt
Gene identifier 947177
Protein name Deoxyguanosinetriphosphate triphosphohydrolase
Protein identifier P15723
Genetic manipulation/variation mutation
Mutation in protein opta 1 mutation