2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000504
Members of this Pool
Members of control pools
POOL000501
Last modified: 10/Sep/2021
Results
Publication
Ahluwalia D, Schaaper RM: Hypermutability and error catastrophe due to defects in ribonucleotide reductase., Proc Natl Acad Sci U S A, 2013

PubMed PMCID
Value 8.4
Dimension %
Error (unspecified) 4.7
Relative compared to ATP
Data presentation in publication numerical
Source
Source organism E. coli (Escherichia coli)
Taxonomy 562
Bacterial or fungal strain NR12470 derivative of strain MG1655
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects Mutation in ribonucleotide reductase specificity-site; mutator phenotype
Genes and Proteins
Gene name nrdA
Gene identifier 946612
Protein name Ribonucleoside-diphosphate reductase 1 subunit alpha
Protein identifier P00452
Genetic manipulation/variation mutation
Mutation in protein A301V