DNTP001928
dTTP
dNTP Pool | |
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Pool identifier | POOL000498 |
Members of this Pool |
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Members of control pools |
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POOL000497 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Bianchi V, Pontis E, Reichard P: Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.,
J Biol Chem, 1986
PubMed |
Value | 124.7883 | Dimension | % |
Error | Error not provided. |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
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Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
Animal strain | Swill albino mice |
Sample source | cell line |
CLO Cell line name | 3T6-Swiss albino cell (CLO:0001356) |
Cell line/type as in publication | 3T6 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Growth conditions | Eagle's modification of Dulbecco's medium, 37°C; 60-70% of cells should be in S phase before treatment |
Treatment | |
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Drug/stress type | drug |
PubChem | 3657 , 5789 |
Applied drug | hydroxyurea, [5-^3H]thymidine |
Treatment details/effects | [5-^3H]thymidine for 10 min; then 3 mM hydroxyurea (HU); 5 min after HU |
Genes and Proteins | |
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No genes or proteins manipulated. | |