DNTP001865
dGTP
dNTP Pool | |
---|---|
Pool identifier | POOL000481 |
Members of this Pool |
|
Members of control pools |
---|
POOL000474 |
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Kumar D, Viberg J, Nilsson AK, Chabes A: Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint.,
Nucleic Acids Res, 2010
PubMed PMCID |
Value | 82.0707 | Dimension | pmol/108 CFU |
Error | Error not provided. |
Data presentation in publication | diagram |
Source | |
---|---|
Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | DKY4 (MATa rnr1-R293A) |
Sample source | strain |
Cell line/type as in publication | prnr1-R293A |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | grown in synthetic complete media without uracil (SC-URA) with 2% galactose (SC-URA+GAL) for at least six generations |
Treatment | |
---|---|
Treatment details/effects | overexpression of mutant Rnr1 |
Genes and Proteins | |
---|---|
Gene name | RNR1 |
Gene identifier | 856801 |
Protein name | ribonucleoside-diphosphate reductase large chain 1 |
Protein identifier | P21524 |
Genetic manipulation/variation | extrachromosomal expression of mutant protein |
Mutation in protein | R293A |