DNTP001743
dTTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL000446 |
| Members of this Pool |
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Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Zhao X, Chabes A, Domkin V, Thelander L, Rothstein R: The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage.,
EMBO J, 2001
PubMed PMCID |
| Value | 58 | Dimension | % |
| Error (standard deviation) | 4 |
| Relative compared to | control (wild type; data not shown) |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
| Bacterial or fungal strain | W1986 (MATa/α mec1-3/+ rad53-1/+ sml1Δ::HIS3/+) |
| Sample source | strain |
| Cell line/type as in publication | mec1-3 |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Remarks to measurement type | Hofer |
| Growth conditions | cultures were grown exponentially at 30°C in YPD medium for >8 generations |
| Treatment |
|---|
| Genes and Proteins | |
|---|---|
| Gene name | mec1 |
| Gene identifier | 852433 |
| Protein name | serine/threonine-protein kinase MEC1 |
| Protein identifier | P38111 |
| Genetic manipulation/variation | mutation |
| Mutation in protein | strains containing the hypomorphic alleles |