2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Bianchi V, Pontis E, Reichard P: Dynamics of the dATP pool in cultured mammalian cells., Exp Cell Res, 1992

PubMed
Value 35.2
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism Chinese hamster (Cricetulus griseus)
Taxonomy 10029
Sample source cell line
Cell line/type as in publication V79 HPRT-
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions cultures containing various drugs were incubated for 3 h with [3H]adenine (15,000 cpm/pmol) and then shifted to nonlabeled conditioned medium
Treatment
Drug/stress type drug
PubChem 439693 , 457964
Applied drug [3H]adenine, deoxycoformycin, aphidicolin
Treatment details/effects [3H]adenine (15,000 cpm/pmol); DNA synthesis inhibition; t= 0
Genes and Proteins
Gene name HPRT
Gene identifier 100769768
Protein name HPRT
Protein identifier P00494
Genetic manipulation/variation mutation
Mutation in protein knock-out