2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000281
Members of this Pool
Members of control pools
POOL000280
Last modified: 10/Sep/2021
Results
Publication
Giacca M, Borella S, Calderazzo F, Bianchi LC, D'Agaro P, Rampazzo C, Bianchi V, Reichard P: Synergistic antiviral action of ribonucleotide reductase inhibitors and 3'-azido-3'-deoxythymidine on HIV type 1 infection in vitro., AIDS Res Hum Retroviruses, 1996

PubMed
Value 53.57
Dimension pmol/106 cell
Error (standard deviation) 1.43
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication CEM neoplastic T lymphocyte
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions Dulbecco's modified Eagle's medium (DMEM)
Treatment
Drug/stress type drug
PubChem 457388
Applied drug AZC
Treatment details/effects 0.25 μM AZC for 3 days, cytidine analogue, cytotoxic through incoproration into RNA and DNA
Genes and Proteins
No genes or proteins manipulated.