Results
Publication	Buckland RJ, Watt DL, Chittoor B, Nilsson AK, Kunkel TA, Chabes A: Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity., PLoS Genet, 2014 PubMed PMCID
Value	1198.08
Dimension	pmol/108 cell
Error (standard error of the mean)	15.38
Data presentation in publication	diagram

Source
Source organism	baker's yeast (Saccharomyces cerevisiae) Taxonomy 4932
Bacterial or fungal strain	rnr1-Y285A msh2∆ (AC402 derivative)
Sample source	strain
Compartment	whole cell

Experiment Details
Measurement type	HPLC-UV
Extraction method	acid extraction
Growth conditions	YPAD, 30 °C

Treatment
Treatment details/effects	deletion of DNA mismatch repair protein MSH2, component of the post-replicative DNA mismatch repair system (MMR); mutation in ribonucleotide reductase responsible for deoxynucleotide synthesis

Genes and Proteins
Gene name	RNR1
Gene identifier	856801
Protein name	Ribonucleoside-diphosphate reductase large chain 1
Protein identifier	P21524
Genetic manipulation/variation	mutation
Mutation in protein	Y285A
Gene name	MSH2
Gene identifier	854063
Protein name	DNA mismatch repair protein MSH2
Protein identifier	P25847
Genetic manipulation/variation	mutation
Mutation in protein	deletion