Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000278
Members of this Pool
Members of control pools
POOL000277
Last modified: 10/Sep/2021
Results
Publication
Buckland RJ, Watt DL, Chittoor B, Nilsson AK, Kunkel TA, Chabes A: Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity., PLoS Genet, 2014

PubMed PMCID
Value 96.15
Dimension pmol/108 cell
Error (standard error of the mean) 5.77
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain msh2∆ (AC402 derivative)
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions YPAD, 30 °C
Treatment
Treatment details/effects deletion of DNA mismatch repair protein MSH2, component of the post-replicative DNA mismatch repair system (MMR)
Genes and Proteins
Gene name MSH2
Gene identifier 854063
Protein name DNA mismatch repair protein MSH2
Protein identifier P25847
Genetic manipulation/variation mutation
Mutation in protein deletion