DNTP001000
dGTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL000248 |
| Members of this Pool |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Poli J, Tsaponina O, Crabbé L, Keszthelyi A, Pantesco V, Chabes A, Lengronne A, Pasero P: dNTP pools determine fork progression and origin usage under replication stress.,
EMBO J, 2012
PubMed PMCID |
| Value | 17.97 | Dimension | pmol/108 cell |
| Error | Error not provided. |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
| Bacterial or fungal strain | pGAL (W1588-4C derivative) |
| Sample source | strain |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Growth conditions | Exponentially growing pGAL cells were cultured for 2 hours with 2% galactose before addition of 100 mM hydroxyurea for 360 min |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 3657 |
| Applied drug | hydroxyurea |
| Treatment details/effects | cells were transformed with an 'empty' pESC-URA vector; inhibition of deoxynuclotide synthesis by hydroxyurea |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |