2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000226
Members of this Pool
Members of control pools
POOL000217
Last modified: 10/Sep/2021
Results
Publication
Poli J, Tsaponina O, Crabbé L, Keszthelyi A, Pantesco V, Chabes A, Lengronne A, Pasero P: dNTP pools determine fork progression and origin usage under replication stress., EMBO J, 2012

PubMed PMCID
Value 157.3
Dimension pmol/108 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain elg1∆ (W303 derivative)
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions YEP medium supplemented with glucose or galactose; cells were synchronized in G1 by adding α-factor for 170 min
Treatment
Drug/stress type drug
PubChem 22461951
Applied drug α-factor
Treatment details/effects synchronization of cells in G1; mutation(s) in Telomere length regulation protein ELG1, involved in maintaining replication fork integrity
Genes and Proteins
Gene name ELG1
Gene identifier 854315
Protein name Telomere length regulation protein ELG1
Protein identifier Q12050
Genetic manipulation/variation mutation
Mutation in protein deletion