Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000216
Members of this Pool
Members of control pools
POOL000213
Last modified: 10/Sep/2021
Results
Publication
Kumar D, Abdulovic AL, Viberg J, Nilsson AK, Kunkel TA, Chabes A: Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools., Nucleic Acids Res, 2011

PubMed PMCID
Value 97.2
Dimension pmol/108 cell
Error Error not provided.
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain rnr1-Q288A (W4069-4C derivative)
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions YPDA medium, 30 °C
Treatment
Treatment details/effects mutation in ribonucleotide reductase responsible for deoxynucleotide synthesis
Genes and Proteins
Gene name RNR1
Gene identifier 856801
Protein name Ribonucleoside-diphosphate reductase large chain 1
Protein identifier P21524
Genetic manipulation/variation mutation
Mutation in protein Q288A