DNTP000858
dGTP
dNTP Pool | |
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Pool identifier | POOL000214 |
Members of this Pool |
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Members of control pools |
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POOL000213 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Kumar D, Abdulovic AL, Viberg J, Nilsson AK, Kunkel TA, Chabes A: Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools.,
Nucleic Acids Res, 2011
PubMed PMCID |
Value | 15 | Dimension | pmol/108 cell |
Error | Error not provided. |
Data presentation in publication | numerical |
Source | |
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Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | rnr1-Y285F (W4069-4C derivative) |
Sample source | strain |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | YPDA medium, 30 °C |
Treatment | |
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Treatment details/effects | mutation in ribonucleotide reductase responsible for deoxynucleotide synthesis |
Genes and Proteins | |
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Gene name | RNR1 |
Gene identifier | 856801 |
Protein name | Ribonucleoside-diphosphate reductase large chain 1 |
Protein identifier | P21524 |
Genetic manipulation/variation | mutation |
Mutation in protein | Y285F |