DNTP000840
dCTP
dNTP Pool | |
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Pool identifier | POOL000210 |
Members of this Pool |
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Members of control pools |
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POOL000207 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Tramentozzi E, Ferraro P, Hossain M, Stillman B, Bianchi V, Pontarin G: The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592.,
Cell Cycle, 2018
PubMed PMCID |
Value | 20.9424 | Dimension | pmol/106 cell |
Error (SD) | 2.5131 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Cell line/type as in publication | Human monocytic cells (THP-1) knock-out for SAMHD1 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | methanol |
Remarks to measurement type | Bianchi (2009) |
Growth conditions | KO THP-1; G1 |
Treatment | |
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Treatment details/effects | perturbation of deoxyguanosine metabolism |
Genes and Proteins | |
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Gene name | SAMHD1 |
Gene identifier | 25939 |
Protein name | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
Protein identifier | Q9Y3Z3 |
Genetic manipulation/variation | mutation |
Mutation in protein | knock-out |