Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000210
Members of this Pool
Members of control pools
POOL000207
Last modified: 10/Sep/2021
Results
Publication
Tramentozzi E, Ferraro P, Hossain M, Stillman B, Bianchi V, Pontarin G: The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592., Cell Cycle, 2018

PubMed PMCID
Value 55.2632
Dimension pmol/106 cell
Error (SD) 6.3158
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication Human monocytic cells (THP-1) knock-out for SAMHD1
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method methanol
Remarks to measurement type Bianchi (2009)
Growth conditions KO THP-1; G1
Treatment
Treatment details/effects perturbation of deoxyguanosine metabolism
Genes and Proteins
Gene name SAMHD1
Gene identifier 25939
Protein name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Protein identifier Q9Y3Z3
Genetic manipulation/variation mutation
Mutation in protein knock-out