2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000203
Members of this Pool
Members of control pools
POOL000202
Last modified: 10/Sep/2021
Results
Publication
Garbacz MA, Cox PB, Sharma S, Lujan SA, Chabes A, Kunkel TA: The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity., Nucleic Acids Res, 2019

PubMed PMCID
Value 427.2977
Dimension pmol/108 CFU
Error (SD) 13.7174
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Sample source strain
Cell line/type as in publication pol2-16
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects lack of Polε catalytic domains (pol2-16) leads to replicationstress
Genes and Proteins
Gene name POL2
Gene identifier 855459
Protein name DNA polymerase epsilon catalytic subunit A
Protein identifier P21951
Genetic manipulation/variation mutation
Mutation in protein region deletion