DNTP000638
dCTP
dNTP Pool | |
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This entry does not belong to any pool in the database. |
Members of control pools |
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POOL000157 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A: Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired.,
Proc Natl Acad Sci U S A, 2017
PubMed PMCID |
Value | 1.2666 | Dimension | pmol/105 cells |
Error (standard error of the mean) | 0.0925 |
Data presentation in publication | diagram |
Source | |
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Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | strains congenic to W1588-4C |
Sample source | strain |
Cell line/type as in publication | D57N crt1∆ sml1∆ rnh201∆ |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Remarks to measurement type | Chabes (2015) |
Growth conditions | N/A |
Treatment | |
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Treatment details/effects | mutation in ribonucleotide reductase responsible for deoxynucleotide synthesis; deletion of transcriptional repressor and protein inhibitor of RNR |
Genes and Proteins | |
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Gene name | rnr1 |
Gene identifier | 856801 |
Protein name | Ribonucleoside-diphosphate reductase large chain 1 |
Protein identifier | P21524 |
Genetic manipulation/variation | mutation |
Mutation in protein | D57N |
Gene name | crt1 |
Gene identifier | 850873 |
Protein name | RFX-like DNA-binding protein RFX1 |
Protein identifier | P48743 |
Genetic manipulation/variation | mutation |
Mutation in protein | deletion |
Gene name | sml1 |
Gene identifier | 854945 |
Protein name | Ribonucleotide reductase inhibitor protein SML1 |
Protein identifier | Q04964 |
Genetic manipulation/variation | mutation |
Mutation in protein | deletion |