2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000147
Members of this Pool
Members of control pools
POOL000141
Last modified: 10/Sep/2021
Results
Publication
Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A: Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired., Proc Natl Acad Sci U S A, 2017

PubMed PMCID
Value 0.1851
Dimension pmol/105 cells
Error (standard error of the mean) 0
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain strains congenic to W1588-4C
Sample source strain
Cell line/type as in publication RNH201+
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Remarks to measurement type Chabes (2015)
Growth conditions N/A
Treatment
Treatment details/effects mutation in ribonucleotide reductase responsible for deoxynucleotide synthesis
Genes and Proteins
Gene name rnr1
Gene identifier 856801
Protein name Ribonucleoside-diphosphate reductase large chain 1
Protein identifier P21524
Genetic manipulation/variation mutation
Mutation in protein Y285A, Q288E