2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000140
Members of this Pool
Members of control pools
POOL000132
Last modified: 10/Sep/2021
Results
Publication
Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H: Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis., Proc Natl Acad Sci U S A, 2017

PubMed PMCID
Value 42
Dimension pmol/108 CFU
Error (SD) 5
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain derivatives of the S288Cstrains RDKY3686
Sample source strain
Cell line/type as in publication dun1∆ ura7∆
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects NTP/dNTP metabolism perturbation
Genes and Proteins
Gene name dun1
Gene identifier 851457
Protein name DNA damage response protein kinase DUN1
Protein identifier P39009
Genetic manipulation/variation mutation
Mutation in protein deletion
Gene name ura7
Gene identifier 852241
Protein name CTP synthase 1
Protein identifier P28274
Genetic manipulation/variation mutation
Mutation in protein deletion