2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000139
Members of this Pool
Members of control pools
POOL000132
Last modified: 10/Sep/2021
Results
Publication
Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H: Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis., Proc Natl Acad Sci U S A, 2017

PubMed PMCID
Value 71
Dimension pmol/108 CFU
Error (SD) 34
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain derivatives of the S288Cstrains RDKY3686
Sample source strain
Cell line/type as in publication dun1∆ gln3∆
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects NTP/dNTP metabolism perturbation
Genes and Proteins
Gene name dun1
Gene identifier 851457
Protein name DNA damage response protein kinase DUN1
Protein identifier P39009
Genetic manipulation/variation mutation
Mutation in protein deletion
Gene name gln3
Gene identifier 856763
Protein name Nitrogen regulatory protein GLN3
Protein identifier P18494
Genetic manipulation/variation mutation
Mutation in protein deletion