2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000137
Members of this Pool
Members of control pools
POOL000132
Last modified: 10/Sep/2021
Results
Publication
Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H: Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis., Proc Natl Acad Sci U S A, 2017

PubMed PMCID
Value 115
Dimension pmol/108 CFU
Error (SD) 12
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain derivatives of the S288Cstrains RDKY3686
Sample source strain
Cell line/type as in publication shm2∆
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects NTP/dNTP metabolism perturbation
Genes and Proteins
Gene name shm2
Gene identifier 850747
Protein name Serine hydroxymethyltransferase
Protein identifier P37291
Genetic manipulation/variation mutation
Mutation in protein deletion