DNTP000539
dTTP
dNTP Pool | |
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Pool identifier | POOL000135 |
Members of this Pool |
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Members of control pools |
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POOL000132 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H: Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.,
Proc Natl Acad Sci U S A, 2017
PubMed PMCID |
Value | 149 | Dimension | pmol/108 CFU |
Error (SD) | 12 |
Data presentation in publication | numerical |
Source | |
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Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | derivatives of the S288Cstrains RDKY3686 |
Sample source | strain |
Cell line/type as in publication | pol3-L612M |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | N/A |
Treatment | |
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Treatment details/effects | polimerase enzyme active site mutation |
Genes and Proteins | |
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Gene name | pol3 |
Gene identifier | 851456 |
Protein name | DNA polymerase delta catalytic subunit |
Protein identifier | P15436 |
Genetic manipulation/variation | mutation |
Mutation in protein | L612M |