Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000134
Members of this Pool
Members of control pools
POOL000132
Last modified: 10/Sep/2021
Results
Publication
Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H: Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis., Proc Natl Acad Sci U S A, 2017

PubMed PMCID
Value 629
Dimension pmol/108 CFU
Error (SD) 37
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain derivatives of the S288Cstrains RDKY3686
Sample source strain
Cell line/type as in publication pol2-M644G
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects polimerase enzyme active site mutation
Genes and Proteins
Gene name pol2
Gene identifier 855459
Protein name DNA polymerase epsilon catalytic subunit A
Protein identifier P21951
Genetic manipulation/variation mutation
Mutation in protein M644G