DNTP000522
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL000131 |
| Members of this Pool |
|
| Members of control pools |
|---|
| POOL000129 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Mannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE, Im M, Flanagan S, Burhans WC, Zeitouni NC, Shewach DS, Mathews CK, Nikiforov MA: Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence.,
Am J Pathol, 2013
PubMed PMCID |
| Value | 50 | Dimension | % |
| Error (SD) | 8 |
| Relative compared to | control |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| Cell line/type as in publication | WI-38 |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Growth conditions | N/A |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 13730 , 5789 , 135398678 , 20471973 |
| Applied drug | dN |
| Treatment details/effects | overexpression from lentiviral vector; Involved in Ras protein signal transduction (dN supplementation experiment) |
| Genes and Proteins | |
|---|---|
| Gene name | HRAS |
| Gene identifier | 3265 |
| Protein name | GTPase Hras |
| Protein identifier | P01112 |
| Genetic manipulation/variation | extrachromosomal expression of mutant protein |
| Mutation in protein | G12V |