Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000127
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Mannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE, Im M, Flanagan S, Burhans WC, Zeitouni NC, Shewach DS, Mathews CK, Nikiforov MA: Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence., Am J Pathol, 2013

PubMed PMCID
Value 100
Dimension %
Error (SD) Error not provided.
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication WI-38
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects transduced with cDNAs for TS, RR1, and RR2; infected with control lentiviral vector two days after infection
Genes and Proteins
Gene name TS
Gene identifier 7298
Protein name TS
Protein identifier P04818
Genetic manipulation/variation extrachromosomal protein expression
Gene name RR1
Gene identifier 6240
Protein name RR1
Protein identifier P23921
Genetic manipulation/variation extrachromosomal protein expression
Gene name RR2
Gene identifier 6241
Protein name RR2
Protein identifier P31350
Genetic manipulation/variation extrachromosomal protein expression