2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000124
Members of this Pool
Members of control pools
POOL000123
Last modified: 10/Sep/2021
Results
Publication
Mannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE, Im M, Flanagan S, Burhans WC, Zeitouni NC, Shewach DS, Mathews CK, Nikiforov MA: Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence., Am J Pathol, 2013

PubMed PMCID
Value 20.17
Dimension %
Error (SD) 3.37
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication WI-38
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects overexpression from lentiviral vector; Involved in Ras protein signal transduction
Genes and Proteins
Gene name HRAS
Gene identifier 3265
Protein name GTPase Hras
Protein identifier P01112
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein G12V