2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000111
Members of this Pool
Members of control pools
POOL000110
Last modified: 10/Sep/2021
Results
Publication
Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA: Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells., Cell Cycle, 2008

PubMed PMCID
Value 2
Dimension fold change
Error (unspecified) 0.15
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Cell line/type as in publication melanocytes
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Remarks to measurement type In the manuscript the authors use both, HPLC-UV and dNTP incorporation assay measurements, but it was not clear which of them has been applied to measure particular dNTP quantities.
Growth conditions N/A
Treatment
Treatment details/effects overexpression of c-myc
Genes and Proteins
Gene name MYC
Gene identifier 4609
Protein name c-myc
Protein identifier P01106
Genetic manipulation/variation extrachromosomal protein expression