2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000108
Members of this Pool
Members of control pools
POOL000106
Last modified: 10/Sep/2021
Results
Publication
Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA: Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells., Cell Cycle, 2008

PubMed PMCID
Value 0.42
Dimension fold change
Error (unspecified) 0.03
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication SK-Mel-19
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Remarks to measurement type In the manuscript the authors use both, HPLC-UV and dNTP incorporation assay measurements, but it was not clear which of them has been applied to measure particular dNTP quantities.
Growth conditions N/A
Treatment
Treatment details/effects IMPDH2-shRNA; Inosine-5'-monophosphate dehydrogenase 2 inhibition
Genes and Proteins
Gene name IMPDH2
Gene identifier 3615
Protein name IMPDH2
Protein identifier P12268
Genetic manipulation/variation silencing