DNTP000428
dCTP
dNTP Pool | |
---|---|
Pool identifier | POOL000107 |
Members of this Pool |
|
Members of control pools |
---|
POOL000106 |
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA: Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells.,
Cell Cycle, 2008
PubMed PMCID |
Value | 0.85 | Dimension | fold change |
Error (unspecified) | 0.03 |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
---|---|
Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Cell line/type as in publication | SK-Mel-19 |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | HPLC-UV |
Extraction method | acid extraction |
Remarks to measurement type | In the manuscript the authors use both, HPLC-UV and dNTP incorporation assay measurements, but it was not clear which of them has been applied to measure particular dNTP quantities. |
Growth conditions | N/A |
Treatment | |
---|---|
Treatment details/effects | TS-shRNA; thymidylate synthase inhibition |
Genes and Proteins | |
---|---|
Gene name | TYMS |
Gene identifier | 7298 |
Protein name | TS |
Protein identifier | P04818 |
Genetic manipulation/variation | silencing |