2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000087
Members of this Pool
Members of control pools
POOL000082 POOL000083
Last modified: 10/Sep/2021
Results
Publication
Angus SP, Wheeler LJ, Ranmal SA, Zhang X, Markey MP, Mathews CK, Knudsen ES: Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication., J Biol Chem, 2002

PubMed
Value 1.4
Dimension pmol/106 cell
Error (unspecified) 1.3
Data presentation in publication diagram
Source
Source organism brown rat (Rattus norvegicus)
Taxonomy 10116
Sample source cell line
Cell line/type as in publication A2-4
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Sherman and Fyfe
Growth conditions asynchronous
Treatment
Drug/stress type drug
PubChem 3385
Applied drug 5-FU
Treatment details/effects proteinexpression; thymidylate synthase inhibition
Genes and Proteins
Gene name RB1
Gene identifier 24708
Protein name PSM-RB
Protein identifier P33568
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein PSM - phosphorylation site mutant