DNTP000348
dCTP
dNTP Pool | |
---|---|
Pool identifier | POOL000087 |
Members of this Pool |
|
Members of control pools | |
---|---|
POOL000082 | POOL000083 |
|
|
Last modified: 10/Sep/2021
Results | |
---|---|
Publication |
Angus SP, Wheeler LJ, Ranmal SA, Zhang X, Markey MP, Mathews CK, Knudsen ES: Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication.,
J Biol Chem, 2002
PubMed |
Value | 64.8 | Dimension | pmol/106 cell |
Error (unspecified) | 9.8 |
Data presentation in publication | diagram |
Source | |
---|---|
Source organism |
brown rat
(Rattus norvegicus)
Taxonomy 10116 |
Sample source | cell line |
Cell line/type as in publication | A2-4 |
Compartment | whole cell |
Experiment Details | |
---|---|
Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | Sherman and Fyfe |
Growth conditions | asynchronous |
Treatment | |
---|---|
Drug/stress type | drug |
PubChem | 3385 |
Applied drug | 5-FU |
Treatment details/effects | proteinexpression; thymidylate synthase inhibition |
Genes and Proteins | |
---|---|
Gene name | RB1 |
Gene identifier | 24708 |
Protein name | PSM-RB |
Protein identifier | P33568 |
Genetic manipulation/variation | extrachromosomal expression of mutant protein |
Mutation in protein | PSM - phosphorylation site mutant |