Results
Publication	Angus SP, Wheeler LJ, Ranmal SA, Zhang X, Markey MP, Mathews CK, Knudsen ES: Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication., J Biol Chem, 2002 PubMed
Value	2.8
Dimension	pmol/106 cell
Error (unspecified)	0.1
Data presentation in publication	diagram

Source
Source organism	brown rat (Rattus norvegicus) Taxonomy 10116
Sample source	cell line
Cell line/type as in publication	A2-4
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	methanol
Remarks to measurement type	Sherman and Fyfe
Growth conditions	asynchronous

Treatment
Drug/stress type	drug
PubChem	126941
Applied drug	MTX
Treatment details/effects	proteinexpression; thymidylate synthase inhibition

Genes and Proteins
Gene name	RB1
Gene identifier	24708
Protein name	PSM-RB
Protein identifier	P33568
Genetic manipulation/variation	extrachromosomal expression of mutant protein
Mutation in protein	PSM - phosphorylation site mutant