2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000047
Members of this Pool
Members of control pools
POOL000041
Last modified: 10/Sep/2021
Results
Publication
Arecco A, Mun BJ, Mathews CK: Deoxyribonucleotide pools as targets for mutagenesis by N-methyl-N-nitrosourea., Mutat Res, 1988

PubMed
Value 1.33
Dimension fold change
Error Error not provided.
Relative compared to control
Data presentation in publication diagram
Source
Source organism Chinese hamster (Cricetulus griseus)
Taxonomy 10029
Sample source cell line
Cell line/type as in publication V79 hamster lung fibroblasts
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Two-step extraction using 60 % aqueous methanol followed by 0.5 N perchloric acid.
Growth conditions Cells were grown as attached cultures in Dulbecco's Modified Eagle Medium containing 5 % fetal calf serum.
Treatment
Drug/stress type drug
PubChem 12699
Applied drug N-methyl-N-nitrosourea
Treatment details/effects Sub-confluent cultures were incubated for 30 min with 0.5 mM N-methyl-N-nitrosourea
Genes and Proteins
No genes or proteins manipulated.