2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL000043
Members of this Pool
Members of control pools
POOL000041
Last modified: 10/Sep/2021
Results
Publication
Arecco A, Mun BJ, Mathews CK: Deoxyribonucleotide pools as targets for mutagenesis by N-methyl-N-nitrosourea., Mutat Res, 1988

PubMed
Value 40
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication numerical
Source
Source organism Chinese hamster (Cricetulus griseus)
Taxonomy 10029
Sample source cell line
Cell line/type as in publication V79 hamster lung fibroblasts
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Two-step extraction using 60 % aqueous methanol followed by 0.5 N perchloric acid.
Growth conditions Cells were grown as attached cultures in Dulbecco's Modified Eagle Medium containing 5 % fetal calf serum.
Treatment
Drug/stress type drug
PubChem 135398592 , 135518164
Applied drug deoxyguanosine, 8-aminoguanosine
Treatment details/effects Sub-confluent cultures were incubated for 30 min with 0.1 mM of the indicated compound(s).
Genes and Proteins
No genes or proteins manipulated.